Research Trials

General Practice Research

The Hadleigh Practice is now “research active”: helping to conduct high-quality clinical research with the National Institute for Health Research to improve NHS care. Participation in a clinical research study is entirely voluntary but can be a rewarding experience.

National Institute for Health Research

Set up in 2006 by the Department of Health, The National Institute for Health Research (NIHR) aims to improve the health and wealth of the nation using Research. To find out more about the work of the NIHR Clinical Research Network go to

What are the Benefits of taking part in research?

  •      Potential access to new treatments and medicines
  •      Ultimately, improved cost-effective access to healthcare for patient
  •      Increased range for skills for staff involved in research including standardised training: Clinical Research is Good Clinical Practice for Research (GCP) training is a requirement for anyone involved in research. GCP is an international standard to which all NHS research is conducted.
  •      GCP Trained Staff: Dr Callum Harmer.

Reduce Carbon Study

This is a randomised control trial to understand whether prescribing of inhalers by clinicians is influenced by knowledge of their carbon footprint. With over 50 million inhalers prescribed in the UK each year inhalers account for about 3% of the carbon footprint of the NHS each year. The NHS long term plan for sustainability has highlighted the urgent need to reduce the carbon impact of inhalers. By taking part in the REDUCE-carbon study we are helping to explore how inhaler choices are made and specifically whether carbon footprint information changes prescribing recommendations.

The Panoramic trial recruitment is now suspended, with no central registration via the trial website for the time being

The PRINCIPLE study is now also closed to recruitment.

The HARMONIE study

RSV (Respiratory Syncytial Virus) is one of the leading causes of hospitalisation in all infants worldwide and affects 90% of children before the age of two. In recent months, there has been a resurgence of RSV following the easing of COVID-19 public health measures.

The HARMONIE study is evaluating the efficacy of nirsevimab, a new immunisation in protecting against this leading causes of infant hospitalisation worldwide.

Participants go through a number of stages from the initial recruitment into the study, to regular monitoring to understand the effect that the immunisation is having.

Babies are randomly selected to determine whether or not they have the immunisation and follow up checks then take place via the study app to determine effectiveness of the vaccine.

The HARMONIE study will last about 12 months for you and your baby, and participation involves the following:

  1. A visit to the study site - This is called the study visit and is when the antibody dose would be given.
  2. Monthly diary for 6 months - You will be asked to answer a short selection of yes/no questions once a month for a 6-month period.

If you are interested in participating, find out more about the HARMONIE study and how to register via:

Please note the Hadleigh Practice is not associated with this study and has not further details or information about it.  Please contact the Harmonie Study team directly if you have any queries.”

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